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Article

Efficacy of exercise in reducing depressive symptoms across 5-HTTLPR genotypes.

Medicine and science in sports and exercise - 1 Nov 2010

Rethorst Chad D, Landers Daniel M, Nagoshi Craig T, Ross Julianna T D

Abstract excerpt

INTRODUCTION: Exercise is effective in the alleviation of depressive symptoms and may have physiological effects similar to those of selective serotonin reuptake inhibitors (SSRI). Recent research has identified the difference in treatment effects across genetic polymorphisms of the serotonin transporter polymorphic region (5-HTTLPR), in which the l allele has been associated with a better response to SSRI...

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PMID: 20351589
DOI: 10.1249/MSS.0b013e3181de7d51

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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