Article
Depressive Symptoms are Associated with low Serotonin Levels in Plasma but are not 5-HTTLPR Genotype Dependent in Older Adults.
The Spanish journal of psychology - 30 Apr 2021
Trujillo-Hernández Pedro Enrique, Sáenz-Galindo Aide, Saucedo-Cárdenas Odila, Villarreal-Reyna María de Los Ángeles, Salinas-Santander Mauricio Andrés, Carrillo-Cervantes Ana Laura, Torres-Obregón Reyna, Esparza-González Sandra Cecilia
Abstract excerpt
Depressive symptoms are diagnosed by physicians using scales but their pathophysiology is unclear. Low serotonin (5-HT) levels play an important role in depression, and the 5-HT transporter (5-HTT) is an important regulator of plasma serotonin levels and reuptake. Additionally, the 5-HTT gene-linked polymorphic region (5-HTTLPR) is associated with depression. The aim was to clarify the roles of plasma serotonin...
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