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Article

Characterization of novel peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) isoform in human liver.

The Journal of biological chemistry - 16 Dec 2011

Felder Thomas K, Soyal Selma M, Oberkofler Hannes, Hahne Penelope, Auer Simon, Weiss Richard, Gadermaier Gabriele, Miller Karl, Krempler Franz, Esterbauer Harald, Patsch Wolfgang

Abstract excerpt

Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a transcriptional coactivator that contributes to the regulation of numerous transcriptional programs including the hepatic response to fasting. Mechanisms at transcriptional and post-transcriptional levels allow PGC-1α to support distinct biological pathways. Here we describe a novel human liver-specific PGC-1α transcript that results from...

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Source

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Identifiers

PMID: 22009745
DOI: 10.1074/jbc.M111.227496
PMCID: PMC3234813

Genes

PGC
FOXO1
PCK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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