Article
PH-domain-driven targeting of collybistin but not Cdc42 activation is required for synaptic gephyrin clustering.
The European journal of neuroscience - 1 Apr 2010
Reddy-Alla Suneel, Schmitt Bertram, Birkenfeld Jörg, Eulenburg Volker, Dutertre Sebastien, Böhringer Christian, Götz Magdalena, Betz Heinrich, Papadopoulos Theofilos
Abstract excerpt
Collybistin (Cb) is a brain-specific guanine nucleotide exchange factor (GEF) that is essential for the synaptic clustering of gephyrin and GABAA receptors in selected regions of the mammalian central nervous system. It has been previously proposed that Cb regulates gephyrin clustering by activat...
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