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Article

Altered synaptic clustering of GABAA receptors in mice lacking dystrophin (mdx mice)

1 Dec 1999

Abstract excerpt

Dystrophin is selectively localized in the postsynaptic density of neurons in cerebral cortex, hippocampus and cerebellum. Here, we show by double-immunofluorescence staining that dystrophin is extensively colocalized with GABAA receptor subunit clusters in these brain regions. To determine the relevance of this observation, we investigated in mdx mice, which provide a model of Duchenne muscular dystrophy,...

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Identifiers

PMID: 10594673
DOI: 10.1046/j.1460-9568.1999.00887.x

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