Article
Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.
Journal of virology - 1 Jun 2010
Paprotka Tobias, Venkatachari Narasimhan J, Chaipan Chawaree, Burdick Ryan, Delviks-Frankenberry Krista A, Hu Wei-Shau, Pathak Vinay K
Abstract excerpt
Xenotropic murine leukemia virus-related virus (XMRV), a gammaretrovirus, has been isolated from human prostate cancer tissue and from activated CD4(+) T cells and B cells of patients with chronic fatigue syndrome, suggesting an association between XMRV infection and these two diseases. Since APOBEC3G (A3G) and APOBEC3F (A3F), which are potent inhibitors of murine leukemia virus and Vif-deficient human...
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