Article
Interactions of murine APOBEC3 and human APOBEC3G with murine leukemia viruses.
Journal of virology - 1 Jul 2008
Rulli Samuel J, Mirro Jane, Hill Shawn A, Lloyd Patricia, Gorelick Robert J, Coffin John M, Derse David, Rein Alan
Abstract excerpt
APOBEC3 proteins are cytidine deaminases which help defend cells against retroviral infections. One antiviral mechanism involves deaminating dC residues in minus-strand DNA during reverse transcription, resulting in G-to-A mutations in the coding strand. We investigated the effects of mouse APOBE...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
