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Article

Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms.

Retrovirology - 24 Jul 2012

Nitta Takayuki, Lee Sangouk, Ha Dat, Arias Maribel, Kozak Christine A, Fan Hung

Abstract excerpt

BACKGROUND: One of the unique features of gammaretroviruses is that they contain an additional extended form of Gag, glyco-gag, which initiates in the leader sequence. MuLV glyco-gag, gPr80Gag, promotes retrovirus replication and disease progression. Although virtually all infectious MuLVs encode glyco-gag, XMRV (xenotropic murine leukemia virus-related virus) lacks the classical gPr80Gag sequence. We examined...

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Identifiers

PMID: 22828015
DOI: 10.1186/1742-4690-9-58
PMCID: PMC3423011

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Source receipt: pubmed, retrieved 7 Sept 2026.

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