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Article

Biology and pathophysiology of the new human retrovirus XMRV and its association with human disease.

Immunologic research - 1 Dec 2010

Rusmevichientong Alice, Chow Samson A

Abstract excerpt

Xenotropic murine leukemia virus-related virus (XMRV) is a new human retrovirus originally identified in prostate cancer patients with a deficiency in the antiviral enzyme RNase L. XMRV has been detected with varying frequencies in cases of prostate cancer and chronic fatigue syndrome (CFS), as well as in a small proportion of healthy individuals. An etiologic link between XMRV infection and human disease,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20717743
DOI: 10.1007/s12026-010-8165-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Biology and pathophysiology of the new human retrovirus XMRV and its association with human disease.PMID 20717743Read ↗

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer.Semantic proximity Read ↗

No evidence of XMRV in prostate cancer cohorts in the Midwestern United States.Semantic proximity Read ↗

Contamination of clinical specimens with MLV-encoding nucleic acids: implications for XMRV and other candidate human retrovirusesSemantic proximity Read ↗

Multiple Integrated Copies and High-Level Production of the Human Retrovirus XMRV (Xenotropic Murine Leukemia Virus-Related Virus) from 22Rv1 Prostate Carcinoma CellsSemantic proximity Read ↗

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue SyndromeSemantic proximity Read ↗

Detection of xenotropic murine leukemia virus-related virus in normal and tumor tissue of patients from the southern United States with prostate cancer is dependent on specific polymerase chain reaction conditions.Semantic proximity Read ↗

Contamination of human DNA samples with mouse DNA can lead to false detection of XMRV-like sequencesSemantic proximity Read ↗

Disease-associated XMRV sequences are consistent with laboratory contaminationSemantic proximity Read ↗

Xenotropic Murine Leukemia Virus–related Gammaretrovirus in Respiratory TractSemantic proximity Read ↗

Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood SamplesSemantic proximity Read ↗

XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors.Semantic proximity Read ↗

Multiple sources of contamination in samples from patients reported to have XMRV infection.Semantic proximity Read ↗

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