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Article

Longitudinal quasispecies analysis of viral variants in HIV type 1 dually infected individuals highlights the importance of sequence identity in viral recombination.

AIDS research and human retroviruses - 1 Mar 2010

Powell Rebecca L R, Lezeau Lynchy, Kinge Thompson, Nyambi Phillipe N

Abstract excerpt

Little is known regarding the likelihood of recombination between any given pair of nonidentical HIV-1 viruses in vivo. The present study analyzes the HIV-1 quasispecies in the C1C2 region of env, the vif-vpr-vpu accessory gene region, and the reverse transcriptase region of pol. These sequences were amplified from samples obtained sequentially over a 12- to 33-month period from five dually HIV-1-infected...

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Identifiers

PMID: 20334562
DOI: 10.1089/aid.2009.0174
PMCID: PMC2864053

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