Extensive recombination among human immunodeficiency virus type 1 quasispecies makes an important contribution to viral diversity in individual patients.

doi:10.1128/JVI.80.5.2472-2482.2006

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Article

Extensive recombination among human immunodeficiency virus type 1 quasispecies makes an important contribution to viral diversity in individual patients.

Journal of virology - 1 Mar 2006

Charpentier Charlotte, Nora Tamara, Tenaillon Olivier, Clavel François, Hance Allan J

Abstract excerpt

Although recombination during human immunodeficiency virus type 1 (HIV-1) replication in vitro and in vivo has been documented, little information is available concerning the extent that recombination contributes to the diversity of HIV-1 quasispecies in the course of infection in individual patents. To investigate the impact of recombination on viral diversity, we developed a technique that permits the isolation...

Topics

Amino Acid Sequence
Drug Resistance, Viral
Evolution, Molecular
Genes, env
Genes, pol
Genetic Variation
Genome, Viral
HIV Infections
HIV Protease
HIV Reverse Transcriptase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HIV-1

Humans

Molecular Sequence Data

Phylogeny

Recombination, Genetic

Selection, Genetic

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 16474154
DOI: 10.1128/JVI.80.5.2472-2482.2006
PMCID: PMC1395372

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