Article
Frequent intra-subtype recombination among HIV-1 circulating in Tanzania.
PloS one - 1 Jan 2013
Kiwelu Ireen E, Novitsky Vladimir, Margolin Lauren, Baca Jeannie, Manongi Rachel, Sam Noel, Shao John, McLane Mary F, Kapiga Saidi H, Essex M
Abstract excerpt
The study estimated the prevalence of HIV-1 intra-subtype recombinant variants among female bar and hotel workers in Tanzania. While intra-subtype recombination occurs in HIV-1, it is generally underestimated. HIV-1 env gp120 V1-C5 quasispecies from 45 subjects were generated by single-genome amplification and sequencing (median (IQR) of 38 (28-50) sequences per subject). Recombination analysis was performed...
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