Article
Multiple-infection and recombination in HIV-1 within a longitudinal cohort of women.
Retrovirology - 3 Jun 2009
Templeton Alan R, Kramer Melissa G, Jarvis Joseph, Kowalski Jeanne, Gange Stephen, Schneider Michael F, Shao Qiujia, Zhang Guang Wen, Yeh Mei-Fen, Tsai Hua-Ling, Zhang Hong, Markham Richard B
Abstract excerpt
BACKGROUND: Recombination between strains of HIV-1 only occurs in individuals with multiple infections, and the incidence of recombinant forms implies that multiple infection is common. Most direct studies indicate that multiple infection is rare. We determined the rate of multiple infection in a longitudinal study of 58 HIV-1 positive participants from The Women's Interagency HIV Study with a richer sampling...
Topics
- Adult
- Cohort Studies
- DNA, Viral
- Drug Users
- Female
- Genetic Variation
- HIV Infections
- HIV-1
- Humans
- Incidence
- Longitudinal Studies