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Article

Altered expression of transforming growth factor-alpha in hereditary rat renal cell carcinoma.

Cancer research - 1 Jun 1991

Walker C, Everitt J, Freed J J, Knudson A G, Whiteley L O

Abstract excerpt

A hereditary form of renal cell carcinoma exists in rats that results from a single gene mutation and is histologically similar to that described in humans. Cell lines derived from these rat tumors were shown to express abundant transforming growth factor-alpha (TGF-alpha) and epidermal growth factor (EGF)-receptor RNA transcripts, but no EGF mRNA. In contrast, normal kidney expressed EGF and EGF-receptor...

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Identifiers

PMID: 2032234

Genes

EGF
NRK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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