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Article

Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development.

Molecular carcinogenesis - 1 Jul 1997

Everitt J I, Walker C L, Goldsworthy T W, Wolf D C

Abstract excerpt

Transforming growth factor-alpha (TGF-alpha) is a multifunctional cell regulatory protein with a wide range of effects on cell growth and differentiation and has been implicated in the neoplastic transformation of a variety of cell types. Altered expression of TGF-alpha and its cognate receptor (epidermal growth factor receptor) is enhanced in human and rat renal cell carcinomas. The objective of the study...

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PMID: 9254888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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