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Article

Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus.

Immunity - 26 Mar 2010

Schlenner Susan M, Madan Vikas, Busch Katrin, Tietz Annette, Läufle Carolin, Costa Celine, Blum Carmen, Fehling Hans Jörg, Rodewald Hans-Reimer

Abstract excerpt

The cellular differentiation pathway originating from the bone marrow leading to early T lymphocytes remains poorly understood. The view that T cells branch off from a lymphoid-restricted pathway has recently been challenged by a model proposing a common progenitor for T cell and myeloid lineages. We generated interleukin-7 receptor alpha (Il7r) Cre recombinase knockin mice and traced lymphocyte development by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20303297
DOI: 10.1016/j.immuni.2010.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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