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Article

Early T Lymphocyte Progenitors

1 Apr 1996

Abstract excerpt

The earliest steps along the pathway leading to T cells in mice and humans are reviewed. These are the steps between the multipotent hemopoietic stem cell (HSC) and the fully committed precursors undergoing T cell receptor (TCR) gene rearrangement. At this level significant differences between adult and fetal lymphopoiesis have been demonstrated. The extent of lymphoid commitment of precursors within bone marrow...

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Identifiers

PMID: 8717506
DOI: 10.1146/annurev.immunol.14.1.29

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