Article
Runx1/Cbfβ2 complexes are required for lymphoid tissue inducer cell differentiation at two developmental stages.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2011
Tachibana Masashi, Tenno Mari, Tezuka Chieko, Sugiyama Machiko, Yoshida Hisahiro, Taniuchi Ichiro
Abstract excerpt
Hematopoietic lymphoid tissue inducer (LTi) cells are essential for the development of secondary lymphoid tissues including lymph nodes and Peyer's patches. Two transcription factors, the helix-loop-helix inhibitor Id2 and the retinoic acid-related orphan receptor γt (Rorγt), have been shown to b...
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