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Article

The A61G EGF polymorphism is associated with development of extraaxial nervous system tumors but not with overall survival.

Cancer genetics and cytogenetics - 1 Apr 2010

Almeida Luciana Oliveira de, Custódio Aline Cadurin, Santos Marcelo José dos, Almeida José R W, Clara Carlos Afonso, Pinto Giovanny Rebouças, Rey Juan A, Casartelli Cacilda

Abstract excerpt

Epidermal growth factor can activate several signaling pathways, leading to proliferation, differentiation, and tumorigenesis of epithelial tissues by binding with its receptor. The EGF protein is involved in nervous system development, and polymorphisms in the EGF gene on chromosome band 4q25 are associated with brain cancers. The purpose of this study was to investigate the association between the...

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Source

Identifiers

PMID: 20303009
DOI: 10.1016/j.cancergencyto.2009.11.013

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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