Article
Association between +61G polymorphism of the EGF gene and glioma risk in different ethnicities: a meta-analysis.
The Tohoku journal of experimental medicine - 1 Dec 2010
Tan Dianhui, Xu Jincheng, Li Yong, Lai Runlong
Abstract excerpt
Epidermal growth factor (EGF) plays a key role in survival of neural and glial precursor cells. The +61A/G polymorphism of the EGF gene is located in the 5'-untranslated region of EGF mRNA and may affect DNA folding or gene transcription, leading to the increase in EGF protein expression. The association between the +61G allele and glioma risk has been widely reported; however, in general the data from published...
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