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Article

Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.

Journal of cancer research and clinical oncology - 1 Aug 2012

da Silveira Francisco das Chagas Abreu, Lopes Bruno de Almeida, da Fonseca Clovis Orlando, Quirico-Santos Thereza, de Palmer Paixão Izabel Christina Nunes, de Amorim Lidia Maria da Fonte

Abstract excerpt

PURPOSE: Malignant gliomas are associated with alteration in EGF/EGFR signaling. Functional EGF+61A>G polymorphism is implicated with risk, recurrence, and progression of glioma. This study aimed to establish a putative association of EGF+61A>G with risk of glioma development, production of angiogenic growth factor EGF, and the response to perillyl alcohol administered by intranasal route. METHODS: The study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22481252
DOI: 10.1007/s00432-012-1203-5

Genes

EGF
EGFR

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Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.PMID 22481252Read ↗

Association between functional EGF+61 polymorphism and glioma risk.Semantic proximity Read ↗

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A functional +61G/A polymorphism in epidermal growth factor is associated with glioma risk among Asians.Semantic proximity Read ↗

Quantitative assessment of the association between +61A>G polymorphism of epidermal growth factor gene and susceptibility to glioma.Semantic proximity Read ↗

Association between the epidermal growth factor +61 G/A polymorphism and glioma risk: a meta-analysis.Semantic proximity Read ↗

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The A61G EGF polymorphism is associated with development of extraaxial nervous system tumors but not with overall survival.Semantic proximity Read ↗

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