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Article

A functional +61G/A polymorphism in epidermal growth factor is associated with glioma risk among Asians.

PloS one - 1 Jan 2012

Xu Xin, Xi Lei, Zeng Jie, Yao Qinhong

Abstract excerpt

BACKGROUND: Epidermal growth factor (EGF), a potent mitogenic protein, plays an important role in the development of cancers, including glioma. Previous studies showed that the EGF +61G/A polymorphism (rs4444903) may lead to an alteration in EGF production and/or activity, which can result in individual susceptibility to glioma. However, published data regarding the association between the +61G/A polymorphism and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22829952
DOI: 10.1371/journal.pone.0041470
PMCID: PMC3400669

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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