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Article

Association between functional EGF+61 polymorphism and glioma risk.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2007

Costa Bruno Marques, Ferreira Paulo, Costa Sandra, Canedo Paulo, Oliveira Pedro, Silva Ana, Pardal Fernando, Suriano Gianpaolo, Machado José Carlos, Lopes José Manuel, Reis Rui Manuel

Abstract excerpt

PURPOSE: Epidermal growth factor (EGF) plays a critical role in cancer. A polymorphism in the EGF gene (EGF+61) may influence its expression and contribute to cancer predisposition and aggressiveness. In the present study, we aimed to elucidate the role of EGF+61 in glioma susceptibility and prognosis. EXPERIMENTAL DESIGN: A case-control study involving 197 glioma patients and 570 controls was done. Univariate...

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Source

Identifiers

PMID: 17473192
DOI: 10.1158/1078-0432.CCR-06-2606

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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