Association between EGF +61 G/A and glioma risk in a Chinese population.

doi:10.1186/1471-2407-10-221

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Article

Association between EGF +61 G/A and glioma risk in a Chinese population.

BMC cancer - 21 May 2010

Wang Shujie, Zhao Yao, Ruan Zhenchao, Chen Hongyan, Fan Weiwei, Chen Juxiang, Wu Qihan, Qian Ji, Zhang Tianbao, Huang Yan, Lu Daru

Abstract excerpt

BACKGROUND: Epidermal growth factor (EGF) is critical in cancer process. EGF and EGF receptor (EGFR) interaction plays a pivotal role in cell proliferation, differentiation, and tumorigenesis of epithelial tissues. Variations of the EGF +61G/A (rs4444903) may lead to an alteration in EGF production and/or activity, which can result in individual susceptibility to brain glioma. The purpose of this study was to...

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Identifiers

PMID: 20487573
DOI: 10.1186/1471-2407-10-221
PMCID: PMC2885363

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EGF
EGFR

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