Article
Association study of an epidermal growth factor gene functional polymorphism with the risk and prognosis of gliomas in Brazil.
The International journal of biological markers - 1 Jan 2000
Pinto Giovanni R, Yoshioka France K N, Clara Carlos A, Santos Marcelo J, Almeida José R W, Burbano Rommel R, Rey Juan A, Casartelli Calcida
Abstract excerpt
Epidermal growth factor (EGF) plays an important role in cancer. A functional single nucleotide polymorphism (SNP) in the 5'-untranslated region of the EGF gene (+61 A>G) may influence its expression and contribute to cancer predisposition and aggressiveness. Aiming to investigate the role of EGF +61 A>G in the susceptibility to glioma and its prognosis, we performed a case-control study with 165 patients and 200...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
