Article
A functional polymorphism in the epidermal growth factor gene is associated with risk for glioma in a Chinese population.
Genetic testing and molecular biomarkers - 1 May 2012
Li Yang, Zhao Yongshun, Liu Jing, Liu Peng, Xu Yinghui
Abstract excerpt
Epidermal growth factor (EGF) plays a key role in survival of neural and glial precursor cells. A single nucleotide polymorphism of the EGF gene +61G/A in the 5'-untranslated region has been reported to be associated with susceptibility to glioma. The purpose of this study was to investigate the potential association between EGF +61G/A and brain glioma in a Chinese population. A case-control study involving 180...
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