Article
Association between the epidermal growth factor +61 G/A polymorphism and glioma risk: a meta-analysis.
PloS one - 1 Jan 2014
Chen Xin, Yang Guang, Zhang Daming, Zhang Weiguang, Zou Huichao, Zhao Hongbo, Zhang Xinjian, Zhao Shiguang
Abstract excerpt
BACKGROUND: Gliomas account for almost 80% of primary malignant brain tumors. Epidermal growth factor (EGF) is an interesting research candidate in which to look for genetic polymorphisms because of its role in mitogenesis and proliferation. Extensive studies have found that a single nucleotide polymorphism (SNP) +61 G/A (rs4444903) in the EGF gene is associated with the susceptibility of glioma, however, the...
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