Article
Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.
BMC medical genomics - 19 Mar 2010
Biong Margarethe, Gram Inger T, Brill Ilene, Johansen Fredrik, Solvang Hiroko K, Alnaes Grethe I G, Fagerheim Toril, Bremnes Yngve, Chanock Stephen J, Burdett Laurie, Yeager Meredith, Ursin Giske, Kristensen Vessela N
Abstract excerpt
BACKGROUND: Increased mammographic density is one of the strongest independent risk factors for breast cancer. It is believed that one third of breast cancers are derived from breasts with more than 50% density. Mammographic density is affected by age, BMI, parity, and genetic predisposition. It is also greatly influenced by hormonal and growth factor changes in a woman's life cycle, spanning from puberty through...
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