Article
IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort.
International journal of cancer - 1 Sept 2010
Verheus Martijn, Maskarinec Gertraud, Woolcott Christy G, Haiman Christopher A, Le Marchand Loïc, Henderson Brian E, Cheng Iona, Kolonel Laurence N
Abstract excerpt
Insulin-like growth factor-I (IGF-I) has mitogenic properties and stimulates cell growth. In this analysis, we investigated the relation between common genetic variation in IGF1, IGFBP1, and IGFBP3, and mammographic density among 819 women of Hawaiian, European, and Japanese ancestry from the Multiethnic Cohort Study. Mammographic density was assessed using a quantitative computer-assisted method. Previously...
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