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Article

Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study.

Breast cancer research : BCR - 1 Jan 2007

Tamimi Rulla M, Cox David G, Kraft Peter, Pollak Michael N, Haiman Christopher A, Cheng Iona, Freedman Matthew L, Hankinson Susan E, Hunter David J, Colditz Graham A

Abstract excerpt

INTRODUCTION: Mammographic density is one of the strongest risk factors for breast cancer and is believed to represent epithelial and stromal proliferation. Because of the high heritability of breast density, and the role of the insulin-like growth factor (IGF) pathway in cellular proliferation and breast development, we examined the association between common genetic variation in this pathway and mammographic...

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Source

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Identifiers

PMID: 17300730
DOI: 10.1186/bcr1655
PMCID: PMC1851377

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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