Article
Breast cancer susceptibility variants and mammographic density phenotypes in norwegian postmenopausal women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2014
Ellingjord-Dale Merete, Grotmol Tom, Lee Eunjung, Van Den Berg David J, Hofvind Solveig, Couto Elisabeth, Sovio Ulla, Dos-Santos-Silva Isabel, Ursin Giske
Abstract excerpt
BACKGROUND: Mammographic density (MD) is one of the strongest known breast cancer risk factors. Twin studies have suggested that a large part of the variation in MD is genetically determined. We hypothesized that breast cancer susceptibility variants may affect MD, and that their effects may be modified by nongenetic factors. METHODS: We assessed MD, using a computer-assisted method, on 2,348 postmenopausal...
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