Article
Association between IGF1 CA microsatellites and mammographic density, anthropometric measures, and circulating IGF-I levels in premenopausal Caucasian women.
Breast cancer research and treatment - 1 Jul 2009
Fehringer Gordon, Ozcelik Hilmi, Knight Julia A, Paterson Andrew D, Boyd Norman F
Abstract excerpt
BACKGROUND: Results from several studies indicate that mammographic density, a strong risk factor for breast cancer, is greater in premenopausal women with higher circulating IGF-I levels. Both mammographic density and circulating IGF-I levels appear to be partly heritable traits. We hypothesized that in premenopausal women, IGF1 variants are associated with circulating IGF-I concentration, which in turn...
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