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Article

Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density.

Breast cancer research and treatment - 1 Nov 2008

Verheus Martijn, McKay James D, Kaaks Rudolf, Canzian Federico, Biessy Carine, Johansson Mattias, Grobbee Diederick E, Peeters Petra H M, van Gils Carla H

Abstract excerpt

INTRODUCTION: High breast density is one of the strongest known risk factors for developing breast cancer. Insulin-like growth factor I (IGF-I) is a strong mitogen and has been suggested to increase breast cancer risk by increasing the amount of dense tissue in the female breast. OBJECTIVES: We wanted to investigate the effect of common variation in the IGF-1 gene on serum IGF-I levels and on breast density....

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Identifiers

PMID: 18064566
DOI: 10.1007/s10549-007-9827-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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