Article
Variation in transcription factor binding among humans.
Science (New York, N.Y.) - 9 Apr 2010
Kasowski Maya, Grubert Fabian, Heffelfinger Christopher, Hariharan Manoj, Asabere Akwasi, Waszak Sebastian M, Habegger Lukas, Rozowsky Joel, Shi Minyi, Urban Alexander E, Hong Mi-Young, Karczewski Konrad J, Huber Wolfgang, Weissman Sherman M, Gerstein Mark B, Korbel Jan O, Snyder Michael
Abstract excerpt
Differences in gene expression may play a major role in speciation and phenotypic diversity. We examined genome-wide differences in transcription factor (TF) binding in several humans and a single chimpanzee by using chromatin immunoprecipitation followed by sequencing. The binding sites of RNA p...
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