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Article

Effects of aldehyde dehydrogenase-2 genetic polymorphisms on metabolism of structurally different aldehydes in human liver.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jan 2002

Wang Rui-Sheng, Nakajima Tamie, Kawamoto Toshihiro, Honma Takeshi

Abstract excerpt

Genotype analysis of the aldehyde dehydrogenase (ALDH)-2 gene was performed using an improved simplified method, and effects of the genotype on the metabolism of a variety of aldehydes in different fractions of human liver cells were investigated. The effects of sex, aging, smoking, drinking alcohol, liver function, and various drugs on ALDH activity were also analyzed. Of the 39 subjects, eight were...

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Source

Identifiers

PMID: 11744614
DOI: 10.1124/dmd.30.1.69

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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