Article
Genetics of autoimmune diseases: insights from population genetics.
Journal of human genetics - 1 Nov 2015
Ramos Paula S, Shedlock Andrew M, Langefeld Carl D
Abstract excerpt
Human genetic diversity is the result of population genetic forces. This genetic variation influences disease risk and contributes to health disparities. Autoimmune diseases (ADs) are a family of complex heterogeneous disorders with similar underlying mechanisms characterized by immune responses against self. Collectively, ADs are common, exhibit gender and ethnic disparities, and increasing incidence. As natural...
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