Article
Gold nanoparticle-based colorimetric assay of single-nucleotide polymorphism of triplex DNA.
Biosensors & bioelectronics - 15 May 2010
Zhu Xiaoli, Liu Yuexing, Yang Jinghua, Liang Zhiqiang, Li Genxi
Abstract excerpt
Triplex DNA technology has been considered as an attractive antigen strategy for the treatment of genetic-based diseases. Assay of the formation of triplex is an important part in the development of triplex technology. In this paper, we present a novel method to assay triplex DNA. The strategy is based on the unspecific interaction between single-stranded triplex-forming oligonucleotide (TFO) and negatively...
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