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Article

DNA dangling-end-induced colloidal stabilization of gold nanoparticles for colorimetric single-nucleotide polymorphism genotyping.

Chemistry (Weinheim an der Bergstrasse, Germany) - 22 Dec 2014

Akiyama Yoshitsugu, Shikagawa Hiroto, Kanayama Naoki, Takarada Tohru, Maeda Mizuo

Abstract excerpt

A single-nucleotide polymorphism (SNP) detection method was developed by combining single-base primer extension and salt-induced aggregation of gold nanoparticles densely functionalized with double-stranded DNA (dsDNA-AuNP). The dsDNA-AuNPs undergo rapid aggregation in a medium of high ionic stre...

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PMID: 25349129
DOI: 10.1002/chem.201404801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25349129-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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