Article
Triplex-forming oligonucleotide target sequences in the human genome.
Nucleic acids research - 1 Jan 2004
Goñi J Ramon, de la Cruz Xavier, Orozco Modesto
Abstract excerpt
The existence of sequences in the human genome which can be a target for triplex formation, and accordingly are candidates for anti-gene therapies, has been studied by using bioinformatics tools. It was found that the population of triplex-forming oligonucleotide target sequences (TTS) is much more abundant than that expected from simple random models. The population of TTS is large in all the genome, without...
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