Article
Interleukin 10 receptor alpha subunit (IL-10RA) gene polymorphism and IL-10 serum levels in Egyptian atopic patients.
Journal of investigational allergology & clinical immunology - 1 Jan 2010
Hussein P Y M, Zahran F, Ashour Wahba A, Ahmad A S, Ibrahiem M M, Shalaby S M, El Tarhouny S A, El Sherbiny H M, Bakr N
Abstract excerpt
OBJECTIVES: To assess the value of serum interleukin (IL) 10 levels as an immunological marker in atopy and to determine the role of an IL-10RA gene single nucleotide polymorphism (SNP) (serine 138-to-glycine exchange [S138G]) in the pathogenesis of atopic diseases. METHODS: Seventy-five patients with atopic disorders were compared with 25 age-matched healthy volunteers. Serum total immunoglobulin (Ig) E and...
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