Article
Association between genes encoding components of the IL-10/IL-0 receptor pathway and asthma in children.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Jun 2011
Hussein Yousri M, Shalaby Sally M, Mohamed Randa H, Hassan Tamer H
Abstract excerpt
BACKGROUND: Asthma is a chronic inflammation of the airways associated with recurrent symptoms that range from mild to debilitating. Interleukin-10 (IL-10) is a cytokine that displays pleiotropic effects in asthma and allergy. OBJECTIVE: To determine whether polymorphisms of IL-10/IL-10R pathway contribute to asthma susceptibility in Egyptian children. METHODS: The IL-10 (-1082G/A), IL-10R1 (G330R), and signal...
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