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Article

Interleukin-10 polymorphisms in Spanish IgA deficiency patients: a case-control and family study.

BMC medical genetics - 27 Jun 2006

Ortiz Javier, Fernández-Arquero Miguel, Urcelay Elena, López-Mejías Raquel, Ferreira Antonio, Fontán Gumersindo, de la Concha Emilio G, Martínez Alfonso

Abstract excerpt

BACKGROUND: IgA deficiency (IgAD) is the most common primary immunodeficiency in Caucasians. Genetic and environmental factors are suspected to be involved in the development of the disease. Interleukin-10 (IL-10) is a cytokine with stimulatory activity on immunoglobulin production and it may be an important regulator in IgAD pathogenesis. The IL-10 gene contains several single nucleotide polymorphisms (SNPs) and...

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Identifiers

PMID: 16803619
DOI: 10.1186/1471-2350-7-56
PMCID: PMC1526417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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