Article
Association of interleukin-10 gene promoter polymorphism in allergic patients.
Genetic testing and molecular biomarkers - 1 Jun 2012
Gaddam Suman Latha, Priya V Hari Sai, Babu B M V Srikanth, Joshi Lavanya, Venkatasubramanian Sambasivan, Valluri Vijayalakshmi
Abstract excerpt
AIM: Allergic diseases are increasing alarmingly worldwide affecting >30% of the population, including India. Allergy is the result of interaction of the epitopes on the protein with the immunoglobulin E (IgE). T helper cell-2 cytokines promote allergen-specific IgE antibody and induce eosinophil-dominated inflammatory tissue responses. Interleukin-10 (IL-10), an antiinflammatory cytokine, plays a major role in...
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