Article
Interleukin-10 gene polymorphisms in recurrent aphthous stomatitis.
Immunological investigations - 1 Jan 2014
Najafi Shamsolmoulouk, Firooze Moqadam Isaac, Mohammadzadeh Mahsa, Bidoki Alireza Zare, Yousefi Hila, Farhadi Elham, Tonekaboni Arghavan, Meighani Ghasem, Amirzargar Ali Akbar, Rezaei Nima
Abstract excerpt
Recurrent aphthous stomatitis (RAS) is a common oral inflammatory disease with unknown etiology in which the immune system seems to have a role in oral tolerance. Interleukin (IL)-10 is a cytokine synthesis inhibitory factor. Single nucleotide polymorphisms (SNPs) of IL10 gene could alter this cytokine production. The aim of this study was to investigate frequencies of IL10 alleles and genotypes in a group of...
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