Article
ADAM33 expression in atherosclerotic lesions and relationship of ADAM33 gene variation with atherosclerosis.
Atherosclerosis - 1 Jul 2010
Holloway John W, Laxton Ross C, Rose-Zerilli Matthew J, Holloway Judith A, Andrews A Lynn, Riaz Zeshan, Wilson Susan J, Simpson Iain A, Ye Shu
Abstract excerpt
A-disintegrin-and-metalloproteinase-domains (ADAMs) are membrane-anchored glycoproteins involved in cell adhesion, cell migration and proteolysis. ADAM15 has been implicated in atherosclerosis, with an effect on vascular smooth muscle cell migration. We investigated whether ADAM33, which is evolutionally closely related to ADAM15, was expressed in atheromas and whether it had an effect on vascular smooth muscle...
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