Article
Engulfment of apoptotic cells in C. elegans is mediated by integrin alpha/SRC signaling.
Current biology : CB - 23 Mar 2010
Hsu Tsung-Yuan, Wu Yi-Chun
Abstract excerpt
BACKGROUND: Engulfment of apoptotic cells is important for cellular homeostasis and the development of multicellular organisms. Previous studies have shown that more than one engulfment receptors act upstream of the conserved signaling module CED-2/CrkII-CED-5/Dock180-CED-12/ELMO for cell corpse removal in C. elegans, but little is known about their identities, except for PSR-1. RESULTS: We show that in C....
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