Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

Cell - 12 Jun 1998

Liu Q A, Hengartner M O

Abstract excerpt

The rapid engulfment (phagocytosis) of cells undergoing programmed cell death (apoptosis) is a fundamental biological process that is not well understood. Here we report the cloning and functional characterization of ced-6, a gene specifically required for the engulfment of apoptotic cells in the nematode C. elegans. The CED-6 protein contains a phosphotyrosine binding domain at its N terminus and a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Apoptosis
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caenorhabditis elegans

Share to Cloning, Molecular

Share to Molecular Sequence Data

Share to Mutation

Share to RNA, Messenger

Source

Identifiers

PMID: 9635426
DOI: 10.1016/s0092-8674(00)81202-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.PMID 9635426Read ↗

Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans.Semantic proximity Read ↗

Phagocytosis promotes programmed cell death in C. elegans.Semantic proximity Read ↗

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.Semantic proximity Read ↗

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.Semantic proximity Read ↗

Engulfment of apoptotic cells in C. elegans is mediated by integrin alpha/SRC signaling.Semantic proximity Read ↗

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.Semantic proximity Read ↗

Programmed cell deathSemantic proximity Read ↗

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans.Semantic proximity Read ↗

The Apoptosome: Heart and Soul of the Cell Death MachineSemantic proximity Read ↗

Both the caspase CSP-1 and a caspase-independent pathway promote programmed cell death in parallel to the canonical pathway for apoptosis in Caenorhabditis elegans.Semantic proximity Read ↗

PDR-1/hParkin negatively regulates the phagocytosis of apoptotic cell corpses in Caenorhabditis elegans.Semantic proximity Read ↗

Caenorhabditis elegans Myotubularin MTM-1 Negatively Regulates the Engulfment of Apoptotic CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.