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Article

Programmed elimination of cells by caspase-independent cell extrusion in C. elegans.

Nature - 9 Aug 2012

Denning Daniel P, Hatch Victoria, Horvitz H Robert

Abstract excerpt

The elimination of unnecessary or defective cells from metazoans occurs during normal development and tissue homeostasis, as well as in response to infection or cellular damage. Although many cells are removed through caspase-mediated apoptosis followed by phagocytosis by engulfing cells, other mechanisms of cell elimination occur, including the extrusion of cells from epithelia through a poorly understood,...

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Identifiers

PMID: 22801495
DOI: 10.1038/nature11240
PMCID: PMC3416925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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