Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

Cell - 12 Jan 2001

Zhou Z, Hartwieg E, Horvitz H R

Abstract excerpt

We cloned the C. elegans gene ced-1, which is required for the engulfment of cells undergoing programmed cell death. ced-1 encodes a transmembrane protein similar to human SREC (Scavenger Receptor from Endothelial Cells). We showed that ced-1 is expressed in and functions in engulfing cells. The CED-1 protein localizes to cell membranes and clusters around neighboring cell corpses. CED-1 failed to cluster around...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Consensus Sequence
Share to Epidermal Growth Factor
Share to Phagocytosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Receptors, Immunologic

Share to Receptors, Lipoprotein

Share to Receptors, Scavenger

Share to Scavenger Receptors, Class B

Share to src Homology Domains

Source

Identifiers

PMID: 11163239
DOI: 10.1016/s0092-8674(01)00190-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.PMID 11163239Read ↗

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.Semantic proximity Read ↗

Phagocytosis promotes programmed cell death in C. elegans.Semantic proximity Read ↗

Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.Semantic proximity Read ↗

Caenorhabditis elegans Myotubularin MTM-1 Negatively Regulates the Engulfment of Apoptotic CellsSemantic proximity Read ↗

Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans.Semantic proximity Read ↗

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans.Semantic proximity Read ↗

Engulfment of apoptotic cells in C. elegans is mediated by integrin alpha/SRC signaling.Semantic proximity Read ↗

Two alternative mechanisms that regulate the presentation of apoptotic cell engulfment signal in Caenorhabditis elegans.Semantic proximity Read ↗

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.Semantic proximity Read ↗

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.Semantic proximity Read ↗

Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells.Semantic proximity Read ↗

The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.