Article
Genetic interaction of DED1 encoding a putative ATP-dependent RNA helicase with SRM1 encoding a mammalian RCC1 homolog in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 27 Nov 1996
Hayashi N, Seino H, Irie K, Watanabe M, Clark K L, Matsumoto K, Nishimoto T
Abstract excerpt
The Saccharomyces cerevisiae temperature-sensitive mutants srm1-1, mtr1-2 and prp20-1 carry alleles of a gene encoding a homolog of mammalian RCC1. In order to identify a protein interacting with RCC1, a series of suppressors of the srm1-1 mutation were isolated as cold-sensitive mutants and one...
Topics
- Cell Cycle Proteins
- Cloning, Molecular
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Genes, Recessive
- Genes, Suppressor
- Guanine Nucleotide Exchange Factors
- Mutation
- Nuclear Proteins
- Phenotype
- RNA Helicases
- RNA Nucleotidyltransferases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Temperature